Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes.

Molecular biology and evolution - 1 Sept 2007

Jiang Cizhong, Han Leng, Su Bing, Li Wen-Hsiung, Zhao Zhongming

Abstract excerpt

CpG islands (CGIs) are often considered as gene markers, but the number of CGIs varies among mammalian genomes that have similar numbers of genes. In this study, we investigated the distribution of CGIs in the promoter regions of 3,197 human-mouse orthologous gene pairs and found that the mouse g...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to DNA Methylation
Share to Dogs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genome

Share to Genome, Human

Share to Promoter Regions, Genetic

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 17591602
DOI: 10.1093/molbev/msm128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17591602-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes.PMID 17591602Read ↗

Divergence of CpG island promoters: a consequence or cause of evolution?Semantic proximity Read ↗

A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters.Semantic proximity Read ↗

Diversification of CpG-Island Promoters Revealed by Comparative Analysis Between Human and Rhesus Monkey Genomes.Semantic proximity Read ↗

CpG island turnover events predict evolutionary changes in enhancer activitySemantic proximity Read ↗

A new class of human CpG island promoters with primate-specific repeatsSemantic proximity Read ↗

Investigating the role of CpG island DNA methylation at 3’UTRs in cancerSemantic proximity Read ↗

A structural split in the human genome.Semantic proximity Read ↗

Human promoter CpG islands contain primate-specific repeats, cluster and resist reprogrammingSemantic proximity Read ↗

Heterotachy in mammalian promoter evolution.Semantic proximity Read ↗

Distinct evolutionary signatures shape depletion and conservation of short tandem repeat motifs in the human genome: insights into beta‑cell function and diabetesSemantic proximity Read ↗

CGGBP1 from higher amniotes restricts cytosine methylation and drives a GC-bias in transcription factor binding sites at repressed promotersSemantic proximity Read ↗

CpG islands and genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.