Article

The Oft-Overlooked Massively Parallel Reporter Assay: Where, When, and Which Psychiatric Genetic Variants are Functional?

2020-02-03

Abstract excerpt

Neuropsychiatric phenotypes have been long known to be influenced by heritable risk factors. The past decade of genetic studies have confirmed this directly, revealing specific common and rare genetic variants enriched in disease cohorts. However, the early hope for these studies—that only a small set of genes would be responsible for a given disorder—proved false. The picture that has emerged is far more complex:...

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Literature Corpus work: d1edcd91-14cc-56d1-8a12-091342a11319
DOI: 10.1101/2020.02.02.931337

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