Article

Apoptosis is increased in cortical neurons of female Marfan Syndrome mice

2024-10-17

Abstract excerpt

Marfan Syndrome (MFS) is an autosomal dominant genetic disorder that affects connective tissue throughout the body due to mutations in the FBN1 gene. Individuals with MFS display symptoms in different organs, particularly in the vasculature, but the mechanisms of this multi-system dysfunction are still under investigation. There is still a gap in our understanding of the impact of monogenic connective tissue aber...

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Literature Corpus work: d1c7fa39-27b4-5cb5-b37b-e6709f374f9f
DOI: 10.1101/2024.10.14.618278

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