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Article

NADPH oxidase 4 attenuates cerebral artery changes during the progression of Marfan syndrome.

American journal of physiology. Heart and circulatory physiology - 1 May 2016

Onetti Yara, Meirelles Thayna, Dantas Ana P, Schröder Katrin, Vila Elisabet, Egea Gustavo, Jiménez-Altayó Francesc

Abstract excerpt

Marfan syndrome (MFS) is a connective tissue disorder that is often associated with the fibrillin-1 (Fbn1) gene mutation and characterized by cardiovascular alterations, predominantly ascending aortic aneurysms. Although neurovascular complications are uncommon in MFS, the improvement in Marfan patients' life expectancy is revealing other secondary alterations, potentially including neurovascular disorders....

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Share to Arterial Pressure
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mechanotransduction, Cellular

Share to NADH, NADPH Oxidoreductases

Share to Stress, Mechanical

Share to Vascular Remodeling

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Source

Identifiers

PMID: 26945079
DOI: 10.1152/ajpheart.00770.2015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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