Article

Human Plasma IgG1 Repertoires are Simple, Unique, and Dynamic

2020-12-16

Abstract excerpt

The human body produces a vast variety of circulating immunoglobulins (Igs) to recognize and combat pathogens and other non-self molecular components. In human plasma the most abundant class of Igs is the immunoglobulin G subclass I (IgG1) 1. Through somatic recombination and hypermutation, our bodies can theoretically produce several billions of distinct IgG1 variants 2,3. The theoretically available IgG1 reperto...

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Literature Corpus work: d1c632d1-8806-5a20-8a55-1bf864e4ca94
DOI: 10.2139/ssrn.3749694

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