Article

IgG1 responses following SARS-CoV-2 infection are polyclonal and highly personalized, whereby each donor and each clone displays a distinct pattern of cross-reactivity against SARS-CoV-2 variants

2022-02-26

Abstract excerpt

Using a recently introduced efficient mass spectrometry-based approach we monitored individual donors’ IgG1 clonal responses in molecular detail, examining SARS-CoV-2 spike-protein-specific IgG1 repertoires. We monitored the plasma clonal IgG1 profiles of 8 donors (4 male and 4 female) who had recently experienced an infection by either the wild type Wuhan Hu-1 virus or one of 3 VOCs (Alpha, Beta and Gamma). In th...

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Literature Corpus work: 3f4fa599-ead5-5708-9a92-a81c0fc1d6aa
DOI: 10.1101/2022.02.24.481778

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