Article

Next-generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire

2021-07-07

Abstract excerpt

<h4>Methods: </h4> of antibody detection are used to assess exposure or immunity to a pathogen. Here, we present Ig-MS , a novel serological readout that captures the immunoglobulin (Ig) repertoire at molecular resolution, including entire variable regions in Ig light and heavy chains. Ig-MS uses recent advances in protein mass spectrometry (MS) for multi-parametric readout of antibodies, with new metrics like Ion...

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Literature Corpus work: fb76fb3f-6860-58c3-8e1f-38c62c57b120
DOI: 10.1101/2021.07.06.21259226

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