Article
[Complex role of the FA proteins in providing genome stability].
Postepy biochemii - 1 Jan 2005
Kluzek Katarzyna, Zdzienicka Małgorzata Z
Abstract excerpt
FA is a rare genetic disorder characterized by developmental abnormalities, bone marrow failure and cancer susceptibility. Cells that are derived from patients with FA display spontaneous chromosomal instability and hypersensitivity to DNA crosslinking agents that is used in FA clinical diagnosti...
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