Article

A role for AMPK in the regulation of mitosis and cytokinesis

2020-01-01

Abstract excerpt

AMP-activated protein kinase (AMPK) has a central role in maintaining cellular energy homeostasis. AMPK is activated allosterically by AMP and signals to inhibit ATP consuming pathways while simultaneously promoting ATP producing pathways. As such AMPK exerts an anti-proliferative effect to induce cell cycle arrest when nutrient resources are limited. Although many of the anti-proliferative effects of AMPK have be...

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Literature Corpus work: d1a33fc0-b1d9-5df2-bb5f-8e6d88114dc5
DOI: 10.5525/gla.thesis.80254

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