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AMP-activated kinase in human spermatozoa: identification, intracellular localization, and key function in the regulation of sperm motility

11 Jul 2016

Abstract excerpt

AMP-activated kinase (AMPK), a protein that regulates energy balance and metabolism, has recently been identified in boar spermatozoa where regulates key functional sperm processes essential for fertilization. This work's aims are AMPK identification, intracellular localization, and their role in human spermatozoa function. Semen was obtained from healthy human donors. Sperm AMPK and phospho-Thr172-AMPK were...

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PMID: 27678462
DOI: 10.4103/1008-682x.185848

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