Article

The toll-like receptor signalling pathway is altered in iPSC-derived cortical networks from people with bipolar disorder

2026-06-11

Abstract excerpt

<h4>Background</h4> Induced pluripotent stem cell (iPSC)-derived brain cells are widely utilized as in vitro models for several neuropsychiatric disorders, as they retain the donor’s genetic profile, offering a unique opportunity to study living human brain cells and perform controlled experimental manipulations. In this study, we conducted whole transcriptome sequencing of cortical networks (co-cultures of neur...

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Literature Corpus work: d17441db-e812-5951-83bb-891b2cedffaa
DOI: 10.64898/2026.06.09.731031

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