Article

Dysregulation of synaptic-related genes of neuroimmune networks within peripheral blood mononuclear cells in major depressive disorder

2024-11-14

Abstract excerpt

<h4>ABSTRACT</h4> Major depressive disorder (MDD) involves complex neuroimmune interactions linked to gene modulation. Our study investigates synaptic-related gene dysregulation in peripheral blood mononuclear cells (PBMCs) from MDD patients, showing how these immune cells mirror neural processes. Using RNA-seq data, we identified 1,383 differentially expressed genes (DEGs) related to neuroimmune crosstalk, with...

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Literature Corpus work: ab59dc8d-e11d-577b-a8b7-fad46ccd5f02
DOI: 10.1101/2024.11.13.623441

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