Article

Neuroimmune transcriptome changes in brains of psychiatric and neurological disorder patients

2022-02-15

Abstract excerpt

Neuroinflammation has been implicated in multiple brain disorders but the extent and the magnitude of change in immune-related genes (IRGs) across distinct brain disorders has not been directly compared. We curated 1,275 IRGs and investigated their expression changes in 2,467 postmortem brains of controls and patients with six major brain disorders, including schizophrenia (SCZ), bipolar disorder (BD), autism spec...

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Literature Corpus work: b89cd819-e9ff-58d8-b4f8-083d78cafd43
DOI: 10.1101/2022.02.14.22269692

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