Article

Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

2019-01-09

Abstract excerpt

Mitophagy is an important quality control mechanism in eukaryotic cells, and defects in mitophagy correlate with aging phenomena and neurodegenerative disorders. It is known that different mitochondrial matrix proteins undergo mitophagy with very different rates, but to date the mechanism underlying this selectivity at the individual protein level has remained obscure. We now present evidence indicating that prote...

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Literature Corpus work: d16f7775-82f7-5c7d-a3ef-ff552da335ff
DOI: 10.1101/513135

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