Article

Simple genetic models for autism spectrum disorder

2015-03-30

Abstract excerpt

To explore the interplay between new mutation, transmission, and gender bias in genetic disease requires formal quantitative modeling. Autism spectrum disorders offer an ideal case: they are genetic in origin, complex, and show a gender bias. The high reproductive costs of autism ensure that most strongly associated genetic mutations are short-lived, and indeed the disease exhibits both transmitted and de novo co...

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Literature Corpus work: d16cbeae-c0a3-5cb8-bfae-dfb7eee8e41c
DOI: 10.1101/017301

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