Article
Quantifying and modeling birth order effects in autism.
PloS one - 1 Jan 2011
Turner Tychele, Pihur Vasyl, Chakravarti Aravinda
Abstract excerpt
Autism is a complex genetic disorder with multiple etiologies whose molecular genetic basis is not fully understood. Although a number of rare mutations and dosage abnormalities are specific to autism, these explain no more than 10% of all cases. The high heritability of autism and low recurrence risk suggests multifactorial inheritance from numerous loci but other factors also intervene to modulate risk. In this...
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