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Epigenome-wide association study identifies<i>TXNIP</i>gene associated with type 2 diabetes mellitus and sustained hyperglycemia

7 Dec 2015

Abstract excerpt

Type 2 diabetes mellitus (DM) is an established risk factor for a wide range of vascular diseases, including ischemic stroke (IS). Glycated hemoglobin A1c (HbA1c), a marker for average blood glucose levels over the previous 12 weeks, is used as a measure of glycemic control and also as a diagnostic criterion for diabetes (HbA1c levels ≥ 6.5%). Epigenetic mechanisms, such as DNA methylation, may be associated with...

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PMID: 26643952
DOI: 10.1093/hmg/ddv493

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