Article
Polymorphisms of ANPEP Gene Are Associated with Microvascular Complications of Type 2 Diabetes.
Bulletin of experimental biology and medicine - 1 Nov 2024
Korvyakova Ya E, Azarova I E, Markina D D, Churilin M I, Bushueva O Yu, Klyosova E Yu, Solodilova M A, Polonikov A V
Abstract excerpt
We studied the association of polymorphisms in the aminopeptidase N gene (ANPEP) with the development of diabetic retinopathy and nephropathy in patients with type 2 diabetes mellitus (T2DM). DNA samples from T2DM patients (n=1425) were genotyped for 23 single nucleotide polymorphisms (SNPs) using the MassARRAY system. Associations of SNP rs13380049 of the ANPEP gene with a lower risk of diabetic retinopathy...
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