Article
IFITMs Inhibit Cell Fusion Mediated by Trophoblast Syncytins
2019-07-24
Abstract excerpt
Type I interferon (IFN) induced by virus infections during pregnancy causes placental damage, though the mechanisms and identities of IFN-stimulated genes that are involved remain under investigation. The IFN-induced transmembrane proteins (IFITMs) inhibit virus infections by preventing virus membrane fusion with cells and by inhibiting fusion of infected cells (syncytialization). Fusion of placental trophoblasts...
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Identifiers and source
- Literature Corpus work
- d1502aa9-2e7c-5837-a1b4-2c216be24c2b
- DOI
- 10.1101/713032
