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Article

Interferon-induced transmembrane proteins inhibit cell fusion mediated by trophoblast syncytins

18 Nov 2019

Abstract excerpt

Type I interferon (IFN) induced by virus infections during pregnancy can cause placental damage, but the mechanisms and identities of IFN-stimulated genes that are involved in this damage remain under investigation. The IFN-induced transmembrane proteins (IFITMs) inhibit virus infections by preventing virus membrane fusion with cells and by inhibiting fusion of infected cells (syncytialization). Fusion of...

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Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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PMID: 31735710
DOI: 10.1074/jbc.ac119.010611

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