Article

A clustered regularly interspaced short palindromic repeats knockout method to reveal methyl-CpG binding domain 4 function

2022-11-14

Abstract excerpt

<title>Abstract</title> DNA methylation is an epigenetic mechanism tailored for DNA repression, engineered for regulating genetic expression without direct manipulation of the nucleotide sequence. One component of this process includes methyl-binding proteins (MBD), which have an affinity for methyl groups, and they competitively inhibit transcription factors from binding with genetic promoters. Interestingly,...

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Literature Corpus work: d14536e4-b4c5-5d68-a860-c842960a67db
DOI: 10.21203/rs.3.rs-2266782/v1

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