Article

Genetic function algorithm (GFA) based QSAR, molecular design, and ADMET screening to assess the antimalarial potential of Amodiaquine derivatives

2024-11-27

Abstract excerpt

The ongoing fight against endemic diseases is complicated by the increasing resistance of malaria parasites to widely used drugs. As a result, the search for more effective antimalarial treatments continues. This research focuses on developing modified Amodiaquine analogues with enhanced efficacy. Additionally, the designed derivatives will be evaluated for their drug-likeness and pharmacokinetic properties. A pre...

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Literature Corpus work: d0ddf98d-b782-5db6-b912-36d4b2954c50
DOI: 10.1016/j.microb.2024.100208

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