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Identification of novel Plasmodium falciparum dihydroorotate dehydrogenase inhibitors for malaria using in silico studies

2022-05-04

Abstract excerpt

Malaria, that ancient infectious disease is considered a great health problem due to its highly infectious and mortality rates . The more harmful kind of malaria is Plasmodium falciparum (Pf), accounting for over 1M fatalities yearly; unfortunately, existing medication regimens are hampered by resistance, necessitating the identification of novel targets against plasmodium species. Since the malaria parasite canno...

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Literature Corpus work
3b3018c6-29ae-5904-9c88-aac660d9994c
DOI
10.1016/j.sciaf.2022.e01214
Open publication

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Identification of novel Plasmodium falciparum dihydroorotate dehydrogenase inhibitors for malaria using in silico studiesDOI 10.1016/j.sciaf.2022.e01214
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