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Article

Driving antimalarial design through understanding of target mechanism.

Biochemical Society transactions - 30 Oct 2020

Calic Petar P S, Mansouri Mahta, Scammells Peter J, McGowan Sheena

Abstract excerpt

Malaria continues to be a global health threat, affecting approximately 219 million people in 2018 alone. The recurrent development of resistance to existing antimalarials means that the design of new drug candidates must be carefully considered. Understanding of drug target mechanism can dramatically accelerate early-stage target-based development of novel antimalarials and allows for structural modifications...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32869828
DOI: 10.1042/BST20200224
PMCID: PMC7609028

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