Article

Impact of regulatory variation across human iPSCs and differentiated cells

2016-12-05

Abstract excerpt

Induced pluripotent stem cells (iPSCs) are an essential tool for studying cellular differentiation and cell types that are otherwise difficult to access. We investigated the use of iPSCs and iPSC-derived cells to study the impact of genetic variation across different cell types and as models for studies of complex disease. We established a panel of iPSCs from 58 well-studied Yoruba lymphoblastoid cell lines (LCLs)...

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Literature Corpus work: d0ab8064-27a9-562d-bc63-f77bb9df4a46
DOI: 10.1101/091660

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