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Article

Integrating Genetics, Transcriptomics, and Proteomics in Lung Tissue to Investigate Chronic Obstructive Pulmonary Disease.

American journal of respiratory cell and molecular biology - 1 Jun 2023

Zhang Yu-Hang, Cho Michael H, Morrow Jarrett D, Castaldi Peter J, Hersh Craig P, Midha Mukul K, Hoopmann Michael R, Lutz Sharon M, Moritz Robert L, Silverman Edwin K

Abstract excerpt

The integration of transcriptomic and proteomic data from lung tissue with chronic obstructive pulmonary disease (COPD)-associated genetic variants could provide insight into the biological mechanisms of COPD. Here, we assessed associations between lung transcriptomics and proteomics with COPD in 98 subjects from the Lung Tissue Research Consortium. Low correlations between transcriptomics and proteomics were...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 36780661
DOI: 10.1165/rcmb.2022-0302OC
PMCID: PMC10257075

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