Article

A non-canonical function for Centromere-associated protein-E (CENP-E) controls centrosome integrity and orientation of cell division

2020-08-14

Abstract excerpt

<h4>Summary</h4> Centromere-associated protein-E (CENP-E) is a kinesin motor localizing at kinetochores. Although its mitotic functions have been well studied, it has been challenging to investigate direct consequences of CENP-E removal using conventional methods because CENP-E depletion results in mitotic arrest. In this study, we harnessed an auxin-inducible degron system to achieve acute degradation of CENP-E....

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Literature Corpus work: d07103e1-de46-5ed0-ac0a-4dcbf1d4d1f1
DOI: 10.1101/2020.08.14.241745

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