Article

<i>DONSON</i> , a gene responsible for microcephalic primordial dwarfism, ensures proper centriole duplication cycle by maintaining centriole engagement during interphase

2020-05-11

Abstract excerpt

Microcephalic primordial dwarfism (MPD) is a genetic disorder characterized by short stature and microcephaly. MPD-related genes are known to regulate centrosome biogenesis, DNA replication or the DNA damage response. Although some of the MPD-related proteins that are implicated in DNA replication localize to centrosomes, how these proteins affect centrosome biogenesis remains mostly elusive. Here, we revisit the...

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Literature Corpus work: 5c7d9c40-8860-5479-b110-6533856a68c3
DOI: 10.1101/2020.05.10.086777

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