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Article

Understanding tolerance to cell wall–active antibiotics

3 Dec 2020

Abstract excerpt

Antibiotic tolerance-the ability of bacteria to survive for an extended time in the presence of bactericidal antibiotics-is an understudied contributor to antibiotic treatment failure. Herein, I review the manifestations, mechanisms, and clinical relevance of tolerance to cell wall-active (CWA) antibiotics, one of the most important groups of antibiotics at the forefront of clinical use. I discuss definitions of...

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PMID: 33274447
DOI: 10.1111/nyas.14541

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