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Article

TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance.

Genome research - 1 Feb 2020

Yasir Muhammad, Turner A Keith, Bastkowski Sarah, Baker David, Page Andrew J, Telatin Andrea, Phan Minh-Duy, Monahan Leigh, Savva George M, Darling Aaron, Webber Mark A, Charles Ian G

Abstract excerpt

Understanding the genetic basis for a phenotype is a central goal in biological research. Much has been learnt about bacterial genomes by creating large mutant libraries and looking for conditionally important genes. However, current genome-wide methods are largely unable to assay essential genes which are not amenable to disruption. To overcome this limitation, we developed a new version of "TraDIS" (transposon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32051187
DOI: 10.1101/gr.254391.119
PMCID: PMC7050523

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