Article

Inhibiting EZH2 complements steroid effects in Duchenne muscular dystrophy

2024-08-22

Abstract excerpt

Duchenne muscular dystrophy (DMD) is a devastating X-linked disorder caused by mutations in the dystrophin gene. Despite recent advances in understanding the disease etiology and applying emerging treatment methodologies, glucocorticoid derivatives remain the only general therapeutic option that can slow disease development. However, the precise molecular mechanism of glucocorticoid action remains unclear, and the...

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Literature Corpus work: d02f1c60-9a35-57c3-b177-e683f307f9d1
DOI: 10.1101/2024.08.22.609220

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