Article

Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells

2002-05-15

Abstract excerpt

We have derived from normal human, mouse, and rat postnatal bone marrow primitive, multipotent adult progenitor cells (MAPCs) that can differentiate into most mesodermal cells and neuroectodermal cells in vitro and into all embryonic lineages in vivo.Here, we show that MAPCs can also differentiate into hepatocyte-like cells in vitro.Human, mouse, and rat MAPCs, cultured on Matrigel with FGF-4 and HGF, differentiat...

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Literature Corpus work: cff35990-8a44-52b1-bcae-383e62c0d196
DOI: 10.1172/jci200215182

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