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Article

Hepatic differentiation of rat induced pluripotent stem cells in vitro.

World journal of gastroenterology - 21 Oct 2015

Sun Chao, Hu Jun-Jie, Pan Qin, Cao Yi, Fan Jian-Gao, Li Guang-Ming

Abstract excerpt

AIM: To show the efficient generation of hepatocyte-like cells (HLCs) differentiated from the induced pluripotent stem cells (iPSCs) of rats. METHODS: Hepatic differentiation was achieved using a three-step protocol with several growth factors. First, rat iPSCs were differentiated into definitive endoderm cells using Activin A and Wnt3a treatment. Then fibroblast growth factor 4 and bone morphogenetic protein 2...

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Identifiers

PMID: 26494966
DOI: 10.3748/wjg.v21.i39.11118
PMCID: PMC4607909

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SRY

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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