Article
Blood-derived stem cells (BDSCs) plasticity: in vitro hepatic differentiation.
Journal of cellular physiology - 1 Jun 2013
Alaimo Giorgia, Cozzoli Eliana, Marfe Gabriella, Esposito Luca, Ranalli Marco, Hmada Dalya, Giordano Antonio, Gambacurta Alessandra
Abstract excerpt
The limited availability of hepatic tissue suitable for the treatment of liver disease and drug research encourages the generation of hepatic-like cells from alternative sources as support for the regenerative medicine. Human blood derived stem cells (BDSCs) express surface markers and genes characteristic of pluripotent stem cells and have the ability to differentiate into different cell types, including tissues...
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