Article

Nodal Modulator is required to sustain endoplasmic reticulum morphology

2021-01-28

Abstract excerpt

Nodal Modulator (NOMO) is a widely conserved type I transmembrane protein of unknown function, with three nearly identical orthologs specified in the human genome. We identified NOMO1 in a proteomics approach aimed at the identification of proteins that support the structural integrity of the endoplasmic reticulum (ER). Overexpression of NOMO1 imposes a sheet morphology on the ER, while depletion of NOMO1 and its...

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Literature Corpus work: cfd1574e-69c2-55f9-9c34-6a8368ae5fc5
DOI: 10.1101/2021.01.28.428001

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