Clusterin: structure, function and roles in disease

Abstract excerpt

Clusterin (CLU) is a glycoprotein that exists in various forms in cells, including nuclear, cytoplasmic, and secreted types. The relative molecular weight of CLU varies significantly due to differences in glycosylation and cleavage. Although CLU is commonly present in mammalian tissues and body fluids, its expression levels differ markedly under physiological and pathological conditions. The existence forms and...

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