Article

Down-regulation of NOX4 expression in dorsal root ganglion of spinal cord could alleviate cancer induced bone pain in rats by reducing oxidative stress response

2020-02-19

Abstract excerpt

<h4>Background: </h4> Cancer-induced bone pain (CIBP) is a common complication in many patients with malignant tumors, and seriously affects their quality of life. Recent studies have implicated reactive oxygen species (ROS) in the perception and regulation of pain through the spinal cord, indicating their possible involvement in CIBP as well. NADPH oxidases (NOX) generate ROS such as H2O2, superoxide anion, nitri...

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Literature Corpus work: cfd0ba5e-7f96-5408-b59b-69cd51b8257e
DOI: 10.21203/rs.2.24002/v1

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