Article
Targeting ferroptosis and immune inflammation: unraveling TLR4's contribution to neuropathic pain pathogenesis
2025-08-21
Abstract excerpt
<title>Abstract</title> <p>This study aims to explore the potential role of ferroptosis in Neuropathic Pain (NP) through bioinformatics analysis. Data from human and rat NP-related datasets (GSE124272 and GSE24982) were analyzed, and differential expression analysis and weighted gene co-expression network analysis were performed to identify key genes associated with NP. Cross-species homology analysis identified...
Topics
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- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Ferroptosis and cancer prognosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neuroinflammation and Neurodegeneration Mechanisms
- Pain Mechanisms and Treatments
- RNA modifications and cancer
- Spine and Intervertebral Disc Pathology
Identifiers and source
- Literature Corpus work
- 4b326f29-4f02-504b-b684-378765912fef
- DOI
- 10.21203/rs.3.rs-6500132/v1
