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Association of HBB gene variants with cardiometabolic and renal phenotypes in a Taiwanese genomic cohort: a cross-sectional study

2026-08-15

Abstract excerpt

Heterozygous mutations in the β-globin gene (HBB) define beta-thalassemia carriers (BTC), a state traditionally regarded as clinically silent. However, the systemic consequences of HBB variant carriage on metabolic and renal phenotypes remain incompletely characterized, particularly in East Asian populations underrepresented in large-scale genomic studies. We performed a cross-sectional study of 478 BTC and 4,780...

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Literature Corpus work
cf97cfe2-c22e-5a22-bac0-749c53e00f1e
DOI
10.1186/s12864-026-13268-8
Open publication

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Association of HBB gene variants with cardiometabolic and renal phenotypes in a Taiwanese genomic cohort: a cross-sectional studyDOI 10.1186/s12864-026-13268-8
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