Article

Association of HBB Gene Variants with Laboratory Profiles and Comorbidities in Taiwanese beta thalassemia carriers: A Case–Control Study

2025-07-28

Abstract excerpt

<title>Abstract</title> <p> Background Heterozygous mutations in the β-globin gene (HBB) underlie beta thalassemia carriers (BTC), traditionally regarded as clinically silent. Emerging data, however, suggest that specific HBB variants may modulate systemic physiology, altering susceptibility to metabolic and renal disorders. Methods We conducted a retrospective case–control study including 478 BTC and 4,780 age-...

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Literature Corpus work: 732f7f92-b8e6-5954-bbc3-a7eb6e9ac3e4
DOI: 10.21203/rs.3.rs-7082804/v1

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