Article
Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans.
Human genetics - 1 Mar 2011
Lo Ken Sin, Wilson James G, Lange Leslie A, Folsom Aaron R, Galarneau Geneviève, Ganesh Santhi K, Grant Struan F A, Keating Brendan J, McCarroll Steven A, Mohler Emile R, O'Donnell Christopher J, Palmas Walter, Tang Weihong, Tracy Russell P, Reiner Alexander P, Lettre Guillaume
Abstract excerpt
Red blood cell, white blood cell, and platelet measures, including their count, sub-type and volume, are important diagnostic and prognostic clinical parameters for several human diseases. To identify novel loci associated with hematological traits, and compare the architecture of these phenotypes between ethnic groups, the CARe Project genotyped 49,094 single nucleotide polymorphisms (SNPs) that capture...
Topics
- Black or African American
- Alpha-Globulins
- Blood Cell Count
- Cohort Studies
- Erythrocyte Count
- Erythrocyte Indices
- Erythrocytes
- Female
- Genetic Association Studies