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HbA1c-based diagnosis of type 2 diabetes and complication risk are distorted in British south Asians due to HbE thalassaemia trait

2026-03-27

Abstract excerpt

<h4>Background</h4> Genetic variants impacting red blood cell biology disrupt the relationship between glycaemia and glycated haemoglobin (HbA1c), with implications for diagnosis and management of type 2 diabetes (T2D). Thalassaemia trait is estimated to affect 350 million people globally, but its impact on T2D and related outcomes is not clear. <h4>Methods</h4> We explored associations between thalassaemia trai...

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Literature Corpus work
6431555d-b04a-597b-bd97-bbd23926cb0c
DOI
10.64898/2026.03.25.26348217
Open publication

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