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Article

Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans.

PloS one - 1 Jan 2016

McLachlan Stela, Giambartolomei Claudia, White Jon, Charoen Pimphen, Wong Andrew, Finan Chris, Engmann Jorgen, Shah Tina, Hersch Micha, Podmore Clara, Cavadino Alana, Jefferis Barbara J, Dale Caroline E, Hypponen Elina, Morris Richard W, Casas Juan P, Kumari Meena, Ben-Shlomo Yoav, Gaunt Tom R, Drenos Fotios, Langenberg Claudia, Kuh Diana, Kivimaki Mika, Rueedi Rico, Waeber Gerard, Hingorani Aroon D, Price Jacqueline F, Walker Ann P

Abstract excerpt

Red blood cell (RBC) traits are routinely measured in clinical practice as important markers of health. Deviations from the physiological ranges are usually a sign of disease, although variation between healthy individuals also occurs, at least partly due to genetic factors. Recent large scale genetic studies identified loci associated with one or more of these traits; further characterization of known loci and...

Topics

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ABO Blood-Group System
DNA Replication
Erythrocytes
Ethnicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Polymorphism, Single Nucleotide

Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 27280446
DOI: 10.1371/journal.pone.0156914
PMCID: PMC4900668

Genes

ABO
HFE
TMPRSS6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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