Article

Metastatic clear-cell renal cell carcinoma: a frequent NOTCH1 mutation predictive of response to anti-NOTCH1 treatment

2022-05-09

Abstract excerpt

<h4>Background: </h4> Despite some improvement in the prognosis of metastatic clear-cell renal cell carcinoma (ccRCC), the identification of new therapeutic targets is essential. Up to now, only limited genomic data has been obtained from metastatic samples. Methods We aimed to characterize metastatic ccRCC by way of whole-genome analyses of metastatic formalin-fixed samples, using OncoScan® technology. We identi...

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Literature Corpus work: cf882456-3eb1-5fd9-9223-a4686051d556
DOI: 10.21203/rs.3.rs-1627883/v1

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