Article

Effective regulatory relationships between genes differ from direct transcription factor-target interactions, and exhibit a distinct statistical signature

2026-04-13

Abstract excerpt

<title>Abstract</title> <p>Gene expression patterns are determined by the interactions between thousands of transcriptional regulators and their target genes. However, mounting evidence of an apparent lack of causal and statistical association between transcription factors and their targets, raises the question of where the effective regulation of any particular gene lies. Using both a simple computational gene r...

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Literature Corpus work: cf68fa10-0d4e-5f51-ad37-7ef44316a3eb
DOI: 10.21203/rs.3.rs-8643144/v1

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