Article

Deletion of Smad3 Protects Against Diabetic Myocardiopathy in db/db Mice 

2020-12-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Diabetic cardiomyopathy (DCM) is a common diabetic complication characterized by diastolic relaxation abnormalities, myocardial fibrosis, and chronic heart failure. Although TGF-b/Smad3 signaling has been shown to play a critical role in chronic heart disease, the role and mechanisms of Smad3 in DCM remain unclear. <bold>Methods:</bold> We generated Smad3 knocko...

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Literature Corpus work: cf59597a-9010-567f-8e2c-061969153e7a
DOI: 10.21203/rs.3.rs-123778/v1

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