Article

KLF15 Negatively Regulates Cardiac Fibrosis and SDF-1β Attenuates Cardiac Fibrosis Through KLF15 Pathway in Type 2 Diabetic Mice

2020-11-24

Abstract excerpt

<h4>Background: </h4> Diabetic cardiomyopathy (DCM) is a common complication in diabetic patients. Cardiac fibrosis is the major pathologic changes, for which the effective and safe approaches remain not available. <h4>Methods: </h4> Wild-type mice and conditional knockout of cardiac specific Klf15 gene ( Klf15 -cKO) mice were fed with either high fat diet (HFD, 60% kcal from fat) or normal diet (ND, 10% kcal from...

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Literature Corpus work: 023c87a0-8043-5b13-84e9-28ec13e5b543
DOI: 10.21203/rs.3.rs-112222/v1

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