Article

Robustness and universality in organelle size control

2019-10-01

Abstract excerpt

<h4>ABSTRACT</h4> One of the grand challenges in quantitative cell biology is understanding the precision with which cells assemble and maintain subcellular organelles. A critical property that governs organelle function is its size. Organelle sizes must be flexible enough to allow cells to grow or shrink them as environments demand, yet be maintained within homeostatic limits. Despite identification of numerous...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cf49ab1e-6d46-5d3c-9ab5-4f8a10f17c3b
DOI: 10.1101/789453

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Robustness and universality in organelle size controlDOI 10.1101/789453Read

Genome dilution by cell growth drives starvation-like proteome remodeling in mammalian and yeast cellsSemantic proximity Read

A Generalized <i>Adder</i> mechanism for Cell Size Homeostasis: Implications for Stochastic Dynamics of Clonal ProliferationSemantic proximity Read

Strongly oversized fission yeast cells lack any size control and tend to grow linearly rather than bilinearly.Semantic proximity Read

Nuclear size control in fission yeast.Semantic proximity Read

Cell enlargement drives aging-associated proteome remodeling and shortens replicative lifespanSemantic proximity Read

Cell length growth patterns in fission yeast reveal a novel size control mechanism operating in late G2 phase.Semantic proximity Read

Size-scaling promotes senescence-like changes in proteome and organelle contentSemantic proximity Read

Organelles - understanding noise and heterogeneity in cell biology at an intermediate scale.Semantic proximity Read

Systematically quantifying morphological features reveals constraints on organoid phenotypes.Semantic proximity Read

Cellular enlargement - A new hallmark of aging?Semantic proximity Read

Cellular intelligence: dynamic specialization through non-equilibrium multi-scale compartmentalizationSemantic proximity Read

Mass Control Genes Buffer a Conserved Sublinear Scaling Law Linking Single-Cell Dry Mass to Mitochondrial Redox EfficiencySemantic proximity Read