Article

Single-cell dynamics of genome-nucleolus interactions captured by nucleolar laser microdissection (NoLMseq)

2024-06-19

Abstract excerpt

Gene position in the nuclear space plays an important role in gene regulation. This is exemplified by repressive chromatin domains frequently contacting nuclear lamina or nucleoli. The nucleolus undergoes structural changes in response to various cellular states, potentially impacting genome organization. However, how the 3D-genome organization responds to nucleolar states has remained underinvestigated due to the...

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Literature Corpus work: cf3bf2c1-ae22-5994-abb5-4513db20d0f3
DOI: 10.1101/2024.06.18.599512

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