Article
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development
1 Jan 2020
Abstract excerpt
Objective: Hepatocellular carcinoma (HCC) is a severely lethal cancer that usually originates from chronic liver injury and inflammation. Although progress on diagnosis and treatment is obvious, the cause of HCC remains unclear. In this study, we sought to determine key genes in HCC development. Methods: To identify key regulators during HCC progression, we performed transcriptome sequencing to obtain time series...
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